In addition, overdosing on nutritional supplements can damage the liver. Herbal and nutritional supplementsĪccording to a 2018 study, some herbal supplements containing aloe vera, cascara, black cohosh, chaparral, and comfrey can be toxic to the liver. Research from 2016 suggests that drug-induced liver toxicity is responsible for 50% of all cases of acute liver failure and 5% of all hospital admissions. Prescription drugs that have associations with liver toxicity include: Other OTC medications that can have this effect include aspirin, ibuprofen, and naproxen. Some prescription and OTC medications can cause liver toxicity, particularly when a person takes them alongside alcohol.Īcetaminophen is the OTC medication that most commonly causes liver toxicity. It can accumulate in the liver, causing permanent scarring and death of the liver cells. The United Kingdom’s National Health Service (NHS) notes that an excessive consumption of alcohol for an extended period can lead to a buildup of toxins that can damage the liver and reduce its ability to regenerate.Īcetaldehyde is the toxic byproduct that occurs when the liver breaks down the alcohol. There are various possible causes of liver toxicity, including those below. monitoring how a person’s symptoms improve after withdrawal from the implicated substance.recommending best practices to stop the exposure.determining the substance that is causing harm to the liver.taking only the recommended dosage of prescription and over-the-counter (OTC) medicationsĪ doctor will take a person’s medical history and ask about any recent medication, as well as herbal and dietary supplements.limiting or avoiding exposure to any toxic substances in the workplace, if possible.refraining from taking any recreational drugs or herbal or nutritional supplements.changing their medication following a doctor’s recommendation.The researchers note that in most cases of liver toxicity, people recover immediately without further treatment after stopping the exposure.ĭepending on the toxin responsible, a person can end their exposure to it by: According to a study in the Journal of Hepatology, discontinuing the implicated drug or agent is the first step in managing liver toxicity.
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